Rufous

ResearchFirst of all, there are a few research nodes that will help you A LOT:Two of these research nodes require good morality points. The pregnancy reduction requires morality to be >20 and the release hub >40 So make sure you are at least 40 morality! (Release hub just to save you time getting rid of animals quickly, breeding through the nursery can crowd pens very quickly)Time SaversSet your nursing time to 0 days:Set your Zoo's hours to the minimum  (more time of the day will be skipped, speeding up pregnancy progression)Build multiple nurseries and CRISPRS in an easily accessible place (preferably near your release hub):I placed three nurseries and 4 CRISPRS because it was the maximum I could reasonably monitor, but feel free to build as many as you like!Throw any and all "new variant" pairs you have from any animal species in. DO NOT TRY TO FOCUS ON ONE GENOME AT A TIME The more new variants you have in pens, the more passive variants you will obtain. Only abort pregnancies with undesired results if your experience bar is full: The experience bar is a lifesaver, especially with larger animals who take a long time to get pregnant, make full use of it!Breed multiples of the same pair:This will make your experience bar go up more quickly, resulting in you getting the variant you need faster. (Especially important when you are down to your last few genomes)CRISPR early, often, and more than you think you will need:  Sometimes especially with the larger animals, it can take FOREVER for one breeding pair to produce more breeding pairs of the same type to make your experience bar go up quickly. Use the CRISPR early as an extra bad luck protection layer. Also, make sure to consider your animal's breeding tree- if one variant is in 5 different breed pairs, account for this.Remove any pairs that are NOT producing a new variantIf you have any pair available that can breed a new variant, make sure to always prioritize that. You only want animals in the nursery that are not producing a new variant when you have extra nursery room, in which case it can be useful to create more new breed pairs.