. 2021 Oct 29;50(2):176-184.
doi: 10.1515/jpm-2021-0215.
Print 2022 Feb 23.
Affiliations
PMID:
34710317
DOI:
10.1515/jpm-2021-0215
Importance of frame rate for the measurement of strain and synchrony in fetuses using speckle tracking echocardiography
Christina Haeger et al.
J Perinat Med.
2021.
Abstract
Objectives:
To assess the influence of frame rate settings on longitudinal strain (LS) and mechanical synchrony (SYN) values in Speckle Tracking Echocardiography (STE) of healthy fetuses.
Methods:
In this prospective study, we collected transversal or apical four-chamber-views of 121 healthy fetuses between 20 and 38 weeks of gestation using three different frame rate (FR) settings (≥ 110, 100 ± 10, 60 ± 10 frames per second). We assessed the segmental and the global LS of both ventricles (2C) and of the left ventricle (LV) offline with QLab 10.8 (Philips Medical Systems, Andover, MA, USA). Inter- and intraventricular SYN were calculated as time difference in peak myocardial strain between the mid-segments of left and right ventricle (interventricular, 2C_Syn) and lateral wall and septum of the left ventricle (intraventricular, LV_Syn), respectively.
Results:
In 84.3% STE was feasible at all three FR settings. The LS increased in both views at higher FRs to a statistically noticeable extent. SYN measurements and the absolute differences at patient level between the FR settings showed no statistically noticeable alterations.
Conclusions:
STE is feasible at low and high FR settings. SYN emerges to be a robust parameter for fetal STE as it is less affected by the FR. High FRs enable high temporal resolutions and thus an accurate examination of fetal hearts. Future research for the technical implementation of tailored fetal STE software is necessary for reliable clinical application.
Keywords:
dyssynchrony; fetal; frame rate; speckle tracking echocardiography; strain; synchrony.
© 2021 Walter de Gruyter GmbH, Berlin/Boston.
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References
Rychik, J, Ayres, N, Cuneo, B, Gotteiner, N, Hornberger, L, Spevak, PJ, et al.. American society of echocardiography guidelines and standards for performance of the fetal echocardiogram. J Am Soc Echocardiogr 2004;17:803–10. https://doi.org/10.1016/j.echo.2004.04.011.
Hoffman, JI, Kaplan, S. The incidence of congenital heart disease. J Am Coll Cardiol 2002;39:1890–900. https://doi.org/10.1016/s0735-1097(02)01886-7.
Steinhard, J, Heinig, J, Schmitz, R, Breithardt, OA, Kiesel, L, Klockenbusch, W. Tissue Doppler imaging of the fetal heart - a new parametric ultrasound technique in prenatal medicine. Ultraschall Med 2007;28:578–83. https://doi.org/10.1055/s-2007-963643.
Verheijen, PM, Lisowski, LA, Stoutenbeek, P, Hitchcock, JF, Brenner, JI, Copel, JA, et al.. Prenatal diagnosis of congenital heart disease affects preoperative acidosis in the newborn patient. J Thorac Cardiovasc Surg 2001;121:798–803. https://doi.org/10.1067/mtc.2001.112825.
Tworetzky, W, McElhinney, DB, Reddy, VM, Brook, MM, Hanley, FL, Silverman, NH. Improved surgical outcome after fetal diagnosis of hypoplastic left heart syndrome. Circulation 2001;103:1269–73. https://doi.org/10.1161/01.cir.103.9.1269.
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